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Previous DBSLS Speakers

Previous DBSLS Speakers
Previous DBSLS Speakers
2024-2025
Itzhak Fried, MD, PhD, FACS
University of California Los Angeles
"Modulation of Human Memory by Deep Brain Stimulation."
Zachary Knight, PhD
University of California San Francisco
Howard Hughes Medical Institutes
"Neural mechanisms that control appetite."
2023-2024
Zhijian 'James' Chen, PhD
University of Texas Southwestern Medical Center
Howard Hughes Medical Institutes
"The enemy within - how does the immune system detect DNA as a danger signal from the interior of a cell?"
Beth Stevens, PhD
Harvard Medical School
Howard Hughes Medical Institutes
"Mapping Microglia States to Function in Development & Disease"
Charles S. Zuker, PhD
Columbia's Zuckerman Institute
"The Body-Brain Axis: From Sugare and Fat to Immunity"
Carrie Bearden, PhD
University of California, Los Angeles
"Pathways to Psychosis in Clinical and Genetic High Risk Youth"
2022-2023
Chuan He, PhD
University of Chicago
Howard Hughes Medical Institute
“RNA Methylation in Gene Expression Regulation”
Paul Bieniasz, PhD
The Rockefeller University
Howard Hughes Medical Institute
"Antibodies versus SARS-CoV-2: Resisting Resistance"
William Hersh, MD, FACMI, FAMIA, FACP
Oregon Health & Science University School Medicine
"Translational Artificial Intelligence; The Need to Translate From Basic Science to Clinical Value"
2021-2022
Lin Tian, PhD
University of California
Davis School of Medicine
"Watching the Brain in Action: Creating Tools for Functional Analysis of Neural Circuitry"
Akiko Iwasaki, PhD
Yale University
Howard Hughes Medical Institute
"Immune Responses to SARS-CoV-2"
Yi Zhang, PhD
Harvard Medical School
Howard Hughes Medical Institute
"Transcriptional Regulation: From Preimplantation to Innate Immunity"
2020-2021
Vamsi Mootha, MD
Harvard Medical School
Massachusetts General Hospital
Howard Hughes Medical Institute
"Hypoxia as a Therapy for Mitochondrial Disease"
Christopher Walsh, MD, PhD
Harvard Medical School
Children's Hospital Boston
"One Braine, Many Genomes: Somatic Mutation and Genomic Diversity in the Human Brain from Development to Degeneration"
Pascale Cossart, PhD
Institut Pasteur
Académie des sciences
"Infection Biology in the Era of Microbiomes: The Listeria Paradigm"
2019-2020
Gökhan Hotamisligil, MD, PhD
Harvard T.H. Chan School of Public Health
"The Metabolic Biology of the Endoplasmic Reticulum in Health and Disease"
Judith Campisi, PhD
Buck Institute for Research on Aging
"Cancer and Aging: Rival Demons"
Jeffrey Friedman, MD, PhD
The Rockefeller University
Howard Hughes Medical Institute
"Leptin and the Homeostatic Control of Food Intake and Body Weight"
Dana Carroll, PhD
Huntsman Cancer Institute
"Genome Editing: A View from the Edge"
2018-2019
Mitchell A. Lazar, MD, PhD
University of Pennsylvania Perelman School of Medicine
"The Ups and Downs of Transcriptional Regulation of Metabolism"
Douglas Lowy, MD
National Cancer Institute, NIH
"Global Control of HPV-associated Cancers by Vaccination and Screening"
Eva Nogales, PhD
HHMI & University of California Berkeley
"Visualizing the molecular machinery in transcription initiation by cryo-EM"
Susan Amara, PhD
National Institute of Mental Health, NIH
"Dyamic regulation of signaling pathways in dopamine neurons: the intracellular actions of amphetamines"
Lily Jan, PhD
HHMI & University of California San Francisco
"The Enigmatic TMEM16 Family"
2017-2018
James McNamara, MD
Duke University School of Medicine
"Neurotrophin Signaling and Epileptogenesis: Mechanistic and Therapeutic Insights"
C. Ronald Kahn, MD
Harvard Medical School
"Plasticity of Adipose Tissue and Its Communication in Metabolic Diseases"
Roger Kornberg, PhD
2006 Nobel Prize in Chemistry
"The Molecular Basis of Eukaryotic Transcription"
Paul Ridker, MD, MPH
Harvard Medical School
"Inflammation and Atherosclerosis: From Population Biology to the Bench to a Novel Treatment"
Duojia Pan, PhD
HHMI and University of Texas Southwestern Medical Center
"Hippo signaling in growth control and beyond"
2016-2017
Wendell Lim, PhD
HHMI and University of California San Francisco
"Synthetic Biology: Learning to Talk to and Program Cells"
Robert Lefkowitz, MD
2012 Nobel Memorial Prize in Chemistry
Duke University School of Medicine
"Seven Transmembrane Receptors"
Barbara Kahn, MD
Harvard Medical School
"Discovery of a Novel Class of Mammalian Lipids with Anti-Diabetic and Anti-Inflammatory Effects"
Christine Seidman, MD
HHMI and Harvard Medical School
"Genetics of Cardiomyopathy: Getting to the Heart of the Matter"
Doris Tsao, PhD
HHMI and California Institute of Technology
"Face Perception: A Window into Visual Object Representation"
2015-2016
Alvin Roth, PhD
2012 Nobel Memorial Prize in Economics
Stanford University
"Market Design and Medical Marketplaces"
Gail Mandel, PhD
HHMI and Oregon Health and Science University
"Repressor Mechanisms and Pathways to Disease
Keith Yamamoto, PhD
University of California San Francisco
"Molecular Signal Processing: From a Steroid Hormone, to Transcriptional Regulatory Networks, to Physiology and Disease, and Back"
"A NextGen Science Enterprise to Move Beyond the Inflection Point"
Angelika Amon, PhD
HHMI and Massachusetts Institute of Technology
"The Causes and Consequences of Aneuploidy"
2014-2015
Steven McKnight, PhD
University of Texas Southwestern Medical Center
"A Solid State Conceptualization of Information Transfer from Gene to Message to Protein"
Ardem Patapoutian, PhD
The Scripps Research Institute and Novartis Research Foundation
"How Do You Feel? Ion Channels Involved in Sensing Mechanical Force"
Evan Eichler, PhD
HHMI and University of Washington
"Autism: New Mutations, Genes and Pathways Indentify Subtypes"
Marc Montminy, MD, PhD
Salk Institute for Biological Studies
"Can You Hear Me Now? Role of the CREB Pathway in Glucose Metabolism"
Eric Olson, PhD
University of Texas Southwestern Medical Center
"The Molecular Pathways of Muscle Development, Disease and Regeneration"
Stanley Hazen, MD, PhD
Cleveland Clinic
"Gut Microbes as a Participant in and Therapteutic Targe for Cardiometabolic Diseases"
2013-2014
Charles Esmon, PhD
Oklahoma Medical Research Foundation
"The role of the protein C pathway and histones in the control of coagulation and inflammation"
Kristi Anseth, PhD
University of Colorado Boulder
"Hydrogels as Mimics of the Extracellular Matrix: Applications in Cell Biology and Tissue Regeneration"
Beth Levine, MD
University Texas Southwestern Medical Center
"Autophagy: Regulation, Physiological Functions, and Roles in Disease"
Carolyn Bertozzi, PhD
University of California Berkeley
"Bioorthogonal Chemistry: From Mechanism to Chemistry"
Samuel Silverstein, MD
Columbia University
"A critical Concentration of effector leukocytes is required to produce sterilizing immunity vs. bacterial and viral infection and cancer"
David Perlmutter, MD
University of Pittsburgh
"The Role of Autophagy in Diseases Caused by Misfolded Proteins: Alpha-1-Antitrypsin Deficiency as Prototype"
2012-2013
Gregory Petsko, DPhil
Weill Cornell Medical College
"Specific Inhibition of Alpha-Synuclein Aggregation as a Therapeutic Strategy for Parkinson's Disease"
James N. Weinstein, DO, MS
Dartmouth-Hitchcock Health Care System
Lebanon Spine Center
"Creating a Sustainable Health Care System: Are You Ready?"
Susan Dymecki, MD, PhD
Harvard Medical School
"Toward Decoding the Brain Serotonergic System: Intersectional Genetics and Functional Probing"
Helen H. Hobbs, MD
University of Texas Southwestern Medical Center
"Nature, Nurture and Fatty Liver Disease"
Stuart A. Lipton, MD, PhD
Sanford Burnham Medical Research Institute
"Protein S-Nitrosylation, Redox Stress and NMDA Receptors in Alzheimer's and Parkinson's Diseases"
2011-2012
C. Ronald Kahn, MD
Harvard University
"Role of Diabetes in Control of Brain Cholesterol Metabolism and Function"
David E. Clapham, MD, PhD
Harvard University
"Novel Ion Channels"
Jay C. Dunlap, PhD
Dartmouth University
"Genetic and Molecular Dissection of a Simple Circadian System"
Beverly S. Mitchell, MD
Stanford University
"Bone Marrow Failure Syndromes Revisted: Therapeutic Implications"
Michael Good, MBBS, PhD, MD, DSc
Griffith University
"The Long Road to a Malaria Vaccine"
Stephen M. Strittmatter, MD, PhD
Yale University
"Cell Surface Interactions during Neurodegeneration and Neural Repair"
2010-2011
Peter C. Doherty, PhD
University of Melbourne, Australia
"Killer Viruses & Killer T-Cells"
Nathaniel Heintz, PhD
The Rockefeller University
"Genetic Dissection of the Mouse Nervous System: Toward a 21st Century Brain Pharmacology"
Erin O'Shea, PhD
Harvard University
"Oscillations and Entrainment in a Three-Protein Circadian Clock"
Toren Finkel, MD, PhD
National Heart, Lung and Blood Institute
"Oxidants, Metabolism & Stem Cell Biology"
Fred H. Gage, PhD
Salk Institute for Biological Studies
"Neuroplasticity & Neurodiversity"
Harald zur Hausen, MD, DSc, MDs
German Cancer Research Centre
2008 Nobel Prize Recipient in Physiology or Medicine
"Perspectives of Tumorvirus Research"
2009-2010
Randy N. Rosier, MD, PhD
University of Rochester
"Translational Research Journeys: From Bedside to the Bench in Skeletal Repair and Arthritis"
E. Peter Greenberg, PhD
University of Washington
"The Social Life of Bacteria"
Pietro DeCamilli, MD
Yale University
"Moelcular Mechanisms of Endocytosis"
C. David Allis, PhD
The Rockefeller University
"Beyond the Double Helix: Reading and Writing the Histone Code"
I. Sadaf Farooqi, PhD, FRCP
University of Cambridge
"Genetic, Molecular & Physiological Mechanisms Involved in Human Obesity"
Harry "Hal" Dietz, MD
Johns Hopkins University
"Marfan Syndrome & Related Disorders: From Molecules to Medicines"
Deepak Srivistava, MD
University of California, San Francisco
"Genetics and Stem Cell Biology in Heart Disease"
Hollis "Holly" Cline, PhD
Scripps Research Institute
"Building Brain Circuits"