Notable and novel scientific awards to celebrate. 

June 2025

New Federal Awards

 
Alexander BoydenPathologyNIH R21
2 years
Gamma herpesvirus impact on required B cell:CD4 T interactions in a B cell-dependent, antibody-independent mouse model of multiple sclerosis
Alexander ClaussenOtolaryngologyNIH K08
5 years
Defining the Mechanisms and Clinical Impact of Neo-ossification after Cochlear Implantation
Karen CyndariEmergency Medicine

NIH K08

5 years

Synovium Immunoprivilege and the Modulation of Resident Synovial Macrophage Functions in Lyme Arthritis
Alexander KleinpeterMicrobiologyNIH R21
2 years
Elucidating the role of IP6 in HIV-1 assembly, maturation, and infection.
Brajesh SinghPediatricsNIH R21
2 years
A membrane fusion apparatus trailblazes measles virus spread in airway cells

David Weiss (Contact PI);

Craig Ellermeier (MPI)

MicrobiologyNIH R01
5 years
Defining the Structure and Function of a New Family of Peptidoglycan Crosslinking Enzymes
Other Awards   
John BernatPediatricsChiesi Farmaceutici S.p.A.
3 years
PegunigaLsidase Alfa in Patients from 2 Years to Less Than 18 Years of Age with Confirmed FabrY Disease
Naomi FeiInternal MedicineHenlius USA Inc.
3 years
HLX22 (Recombinant Humanized Anti-HER2 Monoclonal Antibody Injection) in Combination with Trastuzumab and Chemotherapy (XELOX) versus Trastuzumab and Chemotherapy (XELOX) with or without Pembrolizumab for the First Line Treatment of Locally Advanced or Metastatic Gastroesophageal Junction and Gastric Cancer
Spyridon FortisInternal MedicineGlaxoSmithKline, LLC
3 years
Anti-TSLP Antibody (GSK5784283) in Adults aged 18 to 75 years of age with Uncontrolled Asthma
Muhammad FurqanInternal MedicineBioNTech SE
3 years
BNT327 in combination with chemotherapy and other investigational agents in first-line non-small cell lung cancer
Tara GraffInternal MedicineAbbVie, Inc.
3 years
Epcoritamab + Rituximab and Lenalidomide (R2) compared to Chemoimmunotherapy in Previously Untreated Follicular Lymphoma (EPCORETMFL-2)
Tara GraffInternal MedicineMerck Sharp & Dohme LLC
3 years
Subcutaneous Pembrolizumab Coformulated With Hyaluronidase (MK-3475A) in Participants with Relapsed or Refractory Classical Hodgkin Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-Cell Lymphoma (rrPMBCL)
Tara GraffInternal MedicineMerck Sharp & Dohme LLC
3 years
A Randomized, Open-Label, Multicenter, Phase 2 Study Evaluating theEfficacy and Safety of Zilovertamab Vedotin (MK-2140) Plus R-CHP versus PolatuzumabVedotin plus R-CHP in Treatment-naive Participants with GCB Subtype of Diffuse Large B-Cell Lymphoma (DLBCL).
Alan GundersonInternal MedicineGigaGen Inc
3 years
GIGA-2339 Administered as a Single Ascending Dose and Multiple Ascending Doses in Participants with Chronic Hepatitis B Virus Infection
Henry HoffmanInternal MedicineMeiraGTX, LLC
3 years
Long-term Follow-up of AAV2-hAQP1 Gene Therapy in Participants with Radiation-Induced Late Xerostomia
Matthew KrasowskiPathologyCellaVision
2 years
CellaVision Clinical Studies of DI-90
Yusuf MendaRadiologyNovartis Pharmaceuticals Corporation
4 years
[225Ac] Ac-ETN029 in patients with Advanced DLL3-expressing Solid Tumors
Steven MoorePathologyAvidity Biosciences, Inc.
1 year
Avidity SOW 2
Kenneth NeppleUrologyPfizer Medical Grants & Partnerships (GMGP)
2 years
AI-Enhanced Quality Improvement to Optimize Genetic Testing in Advanced Prostate Cancer
Dimah SaadePediatricsREGENXBIO Inc.
3 years
Intravenous RGX-202 Gene Therapy in Males with Duchenne Muscular Dystrophy (DMD)
Tomohiro TanakaInternal MedicineBluejay Therapeutics, Inc.
3 years
BJT-778 vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (AZURE-1)
Hanna ZembrzuskaInternal MedicineZura BioTibulizumab in Adults  with Systemic Sclerosis

May 2025

New Federal Awards

 
Brad AmendtDental ResearchNIH R56
1 year
Irx1 regulation of oral tissue repair and maintenance.
Competetive Renewal  
Kris DeMaliBiochemistry & Molecular BiolNIH R35
5 years
Molecular Mechanisms Underlying E-cadherin Mechanotransduction
Quanhathai KaewpoowatInternal MedicineUS Department of Health & Human Services, Health Resources & Services Administration
3 years
OP EARLY INTERVENTION SERVICES WITH RESPECT TO HIV DISEASE
Other Awards   
Po Hein EarSurgeryNeuroendocrine Tumor Rsearch Foundation
2 years
Role of NRF2 in SBNETs and development of a novel inhibitor
Mark GrannerNeurologyNeuron Therapeutics Inc
5 years
Inhibitory Interneurons (NRTX-1001) for the Treatment of Drug-resistant Bilateral Temporal Lobe Focal Seizures
Douglas LauxInternal MedicineOncoResponse
3 years
OR502 Alone and in Combination with other Anti-cancer Agents in Subjects with Advanced Malignancies
Paul McCrayPediatricsCystic Fibrosis Foundation
3 years
Optimizing Delivery of Prime Editors to Repair the CFTR F508del Mutation
Mohamad MokademInternal MedicineNovo Nordisk Pharmaceuticals, Inc.
3 years
Testing peripheral nervous system as mediators of the metabolic effects of Monlunabant
Eric MouInternal MedicineCorvus Pharmaceuticals, Inc.
3 years
Soquelitinib versus physician's choice standard of care (SOC) treatment (selected single agents) in participants with relapsed/refractory (R/R) peripheral T-cell lymphoma not otherwise specified (PTCL-NOS), follicular helper T-cell lymphomas (FHTCLs), or systemic anaplastic large-cell lymphoma (sALCL).
Sneha PhadkeInternal MedicineBeOne Medicines USA, Inc.
4 years
BGB-21447 (Bcl-2i) Combinations for Patients With HR+/HER2- Metastatic Breast Cancer
Edgar SamaniegoNeurologyRapid Pulse
3 years
RapidPulseTM Aspiration System as Frontline Approach for Patients with Acute Ischemic Stroke due to Large Vessel Occlusions ("RapidPulse Pivotal Study")
Hira ShaikhInternal MedicineAstraZeneca Pharmaceuticals LP
3 years
GC012F, a Chimeric Antigen Receptor T-cell (CAR T) Therapy Targeting CD19 andB-cell Maturation Antigen (BCMA) in Subjects with Relapsed/Refractory Multiple Myeloma
Patrick SinnPediatricsCystic Fibrosis Foundation
3 years
Chimeric Adenoviral Vectors for Improved Base Editor Delivery to Primate Airways
Lucy WibbenmeyerSurgerySkingenix Inc.
3 years
Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns.

April 2025

New Federal Awards

 
Nagalakshmi BalasubramanianCardiothoracic SurgeryNIH K99
2 years
Alcohol-Induced Metabolome-Epigenome Dysfunction and Alzheimer's Disease Risk
Ryan BoudreauInternal MedicineNIH R35
7 years
Genetic and Molecular Mechanisms of Heart Disease
Amanda DudekMicrobiologyNIH R00
3 years
Mechanisms that Enhance and Suppress HIV-1 Resistance in Gene Edited Primary Human Cells
Amelia Hurley-NovatnyOrthopedic SurgeryNIH F30
4 years
Investigating the role of FGF21 in bone homeostasis in Duchenne Muscular Dystrophy
Nicholas SchnickerMedicine AdministrationNIH S10
1 year
Acquisition of 200 kV Glacios Cryo-TEM at the University of Iowa
Adele StewartNeuroscience & PharmacologyNIH R21
2 years
Sex-biased, region-specific regulation of DA release and clearance
Robert WeissInternal MedicineNIH S10
1 year
High Resolution Research Ultrasound
Competetive Renewal  
Kalpaj ParekhCardiothoracic SurgeryNIH R01
4 years
Pathogenesis of Airway Stem Cell Abnormalities in Obliterative Bronchiolitis
Other Awards   
Caryn BerkowitzInternal MedicineCorMedix Inc.
3 years
DefenCath in Reducing Central Line-Associated Bloodstream Infections (CLABSIs) in Adult Participants Receiving Total Parental Nutrition (TPN) via Central Venous Catheter (CVC)
Muhammad FurqanInternal MedicineSanofi US Serices Inc.
3 years
SAR445877 administered as monotherapy or in combination with other anticancer therapies in adults with advanced solid tumors
Tara GraffInternal MedicineAstraZenica LP
4 years
AZD0486 in Participants with Relapsed or Refractory B-cell Non-Hodgkins Lymphoma (SOUNDTRACK-B)
James HolmesRadiologyUniversity of Virginia
1 year
Model Based Deep Learning Framework for Ultra-High Resolution Multi-Contrast MRI
Asad JavedInternal MedicineIDEAYA Biosciences Inc.
3 years
IDE196 in patients with solid tumors harboring GNAQ/11 mutations or PRKC infusions
Douglas LauxInternal MedicineBicara Therapeutics
3 years
Ficerafusp Alfa (BCA101) or Placebo in Combination with  Pembrolizumab for First-Line Treatment of PD-L1-positive,  Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Vincent MagnottaRadiologyUniversity of Virginia
5 years
Fast Multi-dimensional Diffusion MRI with Sparse Sampling and Model-based Deep Learning Reconstruction
John RiethInternal MedicineSERVIER Bio-Innovation LLC
3 years
Ivosidenib in participants 18 years of age with locally advanced or metastatic conventional chondrosarcoma with an IDH1 mutation, untreated or previously treated with 1 systemic treatment regimen
Edgar SamaniegoNeurologyMedtronic, Inc.
3 years
Clinical Investigation Plan of the Artisse Intrasaccular Device IDE
Edgar SamaniegoNeurologyTerumo Neuro
4 years
Complex Aneurysm Registry (CAR) Real-World Evidence Data Collection for Intracranial Aneurysm Treatment Devices
Antonio SanchezInternal Medicine89bio, Inc.
4 years
Pegozafermin in Subjects with Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis (ENLIGHTEN-Fibrosis)
Jennifer StreeterInternal MedicineAsklepios BioPharmaceutical, Inc.GenePHIT
Michael TanseyPediatricsBioMarin Pharmaceutical, Inc.
3 years
 Growth in Children with Idiopathic Short Stature

March 2025

New Federal Awards

 
Scott Moye-RowleyMolecular Physiology & BiophysicsNIH R21
2 years
Nanobody-mediated proteolysis of Aspergillus fumigatus transcription factors in vitro and in vivo

Robert Mullins (Contact PI);


Budd Tucker (MPI)

Ophthalmology and Visual SciNIH R01
5 years
Editing AMD Risk Alleles in Human Cells
Sarah ShortInternal MedicineNIH R03
2 years
Epithelial specific roles for GPx1 in the intestinal microenvironment
Long-Sheng SongInternal MedicineNIH R01
3 years
Junctophilin-1 in the heart
Ian ThornellInternal MedicineNIH R01
4 years
Receptor-mediated Control of Pulmonary Ionocytes
Other Awards   
Marcelo CorreiaInternal MedicineNovartis Pharmaceuticals CorporationEvaluating INClisiran as a soLUtion to improve LDL-C management and cloSe care gaps in an Inclusive ASCVD and ASCVD risk equivalent population
John EngelhardtAnatomy and Cell BiologyRecode Therapeutics Inc.Recode Scope of Work No 2
Umar FarooqInternal MedicineCelgene/ Bristol-Myers SquibbJCAR017 IN ADULT SUBJECTS WITH RELAPSED OR REFRACTORY INDOLENT B-CELL NON-HODGKIN LYMPHOMA (NHL) (TRANSCEND FL)
Andrew FeiderAnesthesiaMassachusetts General HospitalMinimizing ICU Neurological Dysfunction with Dexmedetomidine-induced Sleep (MINDDS II)
Alicia GerkeInternal MedicinePulmovant, Inc.Mosliciguat in Participants with Pulmonary Hypertension Associated with Interstitial Lung Disease
Michael HummelRadiologyABK Biomedical USA, Inc.Radioembolization Oncology Trial Utilizing Transarterial Eye90 (ROUTE 90) for the Treatment of Hepatocellular Carcinoma (HCC)
Yusuf MendaRadiologyPerspective Therapeutics[212Pb]VMT--NET Targeted Alpha-Particle Therapy for Advanced SSTR2 Positive Neuroendocrine Tumors
Kelly MulfaulNeuroscience & PharmacologyEdward N. & Della L. Thome Memorial FoundationElucidating choroidal CCL5-CCR5 signaling to develop therapeutic targets for early AMD
John RiethInternal MedicinePHILOGEN S.p.A.Doxorubicin and the tumor-targeting human antibody-cytokine fusion protein L19TNF to doxorubicin along as first-line therapy in patients with metastatic leiomyosarcoma
Andrew RussoMolecular Physiology & BiophysVedana Therapeutics, Inc.Characterization of antibody and antibody-like molecules for their ability to reduce light-induced migraine-like phenotypes
Hanna ZembrzuskaInternal MedicineCullinan Therapeutics, IncCLN-978 for the Treatment of Moderate to Severe Systemic Lupus Erythematosus (SLE)", CLN-978-SL-101

February 2025

New Federal Awards

 

Budd Tucker (Contact PI);

Edwin Stone (MPI);

Robert Mullins (MPI)

Ophthalmology and Visual SciNIH R01
5 years
Non-destructive assessment of retinal differentiation capacity and developmental maturity

Mark Greiner (Contact PI):

Aliasger Salem (MPI)

Ophthalmology and Visual Sci

NIH R01

5 years

Modulating Ferroptosis in Fuchs Endothelial Corneal Dystrophy
Competitive Renewal  
Nandakumar NarayananNeurologyNIH R01Frontal Midline delta/theta rhythms and cognitive control in PD
Other Awards   
Tara GraffInternal MedicineBeiGene Ltd.
3 years
Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Patients With Previously Untreated Chronic Lymphocytic Leukemia
Eric MouInternal MedicineMarch Biosciences
6 years
MB-105 in patients with CD5 positive (CD5+) relapsed / refractory T-cell lymphoma (r/r TCL).
Lama NoureddineInternal MedicineAlexion Pharmaceuticals, Inc.
3 years
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ravulizumab in Adult Participants with Immunoglobulin A Nephropathy (IgAN)
Michael TanseyPediatricsNovo Nordisk Pharmaceuticals, Inc.Weight Maintenance in Adolescents With Obesity; Long-Term Treatment With Semaglutide s.c. 2.4 mg Once-weekly
Michael WallOphthalmology and Visual SciAbbVie, Inc.
1 year
AGN-193408 SR in Participants with Open-Angle Glaucoma or Ocular Hypertension

David Stolz (Contact PI);

Daniel Cook, (MPI)

Internal MedicineCystic Fibrosis Foundation
3 years
Iowa CFF RDP Junior Faculty Recruitment Award

January 2025

New Federal Awards

 
Amy RyanAnatomy and Cell BiologyNSF
3 years
Collaborative Research: ENG-BIOTECH: Engineering Biomedical Systems to Investigate Extracellular Matrix Regulation of Airway Basal Cell Stemness and Differentiation

Punam Saha (Contact PI);

Alejandro Comellas Freymond (MPI)

RadiologyNIH R21
2 years
Osteoporosis and Sarcopenia in COPD and CT-based Phenotypes
Other Awards   
Paari DominicInternal MedicineTexas Cardiac Arrhythmia Research FoundationSafety and efficacy of pulsed-field ablation for atrial fibrillation in high versus low-volume ablation centers (SAFFICIENT)
Naomi FeiInternal MedicinePlanes Therapeutics, Inc.PT886 followed by a Multi-cohorT Study in Patients With Advanced GastrIc, Gastroesophageal JuNction (GEJ), or Pancreatic Ductal AdEnocarcinomas of PT886, in Combination with either ChemotherApy, and/or the ChecKpoint Inhibitor Pembrolizumab.
Henry HoffmanOtolaryngologyRiboX Therapeutics, Ltd. (US)RXRG001 to Parotid Gland(s) in Adults with Radiation-Induced Xerostomia and Hyposalivation
Katherine MathewsPediatricsAvidity Biosciences, Inc.AOC 1020 Administered Intravenously to Adult Participants with Facioscapulohumeral Muscular Dystrophy (FSHD)

Eric Taylor (Contact PI);

Douglas Spitz (MPI)

Molecular PhysiologyNationwide Children's HospitalTargeting Tubular Mitochondrial Superoxide Dismutation in Cisplatin Renal Repair
Christopher StrouseInternal MedicineJanssen Research & Development, Inc
5 years
JNJ-68284528, a Chimeric Antigen Receptor T cell (CAR-T) Therapy Directed Against BCMA in Subjects with Multiple Myeloma
Tracey ChoNeurologySanofi US Services, Inc
5 years
Frexalimab (SAR441344) to Terifluomide (Aubagio) in Adult Participants with Relapsing Forms of Multiple Sclerosis
Tracey Cho NeurologySanofi US Services, Inc
5 years
Frexalimab (SAR441344) to Placebo in Adult Participants with Nonrelapsing Secondary Progressive Multiple Sclerosis
Katherine MathewsPediatricsAvidity Biosciences, Inc
5 years
AOC 1044 Administered Intravenously to Healthy Adults
Val SheffieldPediatricsCRISPR Therapeutics, Inc
2 years
MYOC gene editing for Myocilin Associated Glaucoma
    

 

Previous Awards:

2024
2023
2022

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